C11orf94

Across TCGA patient cohorts, C11orf94 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf94-associated genes across cancer lineages are RTL4, SNORD31B, and RNU6-650P. Each is linked with C11orf94 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf94-to-partner and partner-to-C11orf94 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RTL4 grouped by C11orf94-low versus C11orf94-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf94→partner) and Y-score (partner→C11orf94) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RTL4 →	+0.082	+3.888	.004	.002	3	1
UCEC	SNORD31B →	+0.381	+4.582	.002	.005	3	1
UCEC	RNU6-650P →	+0.390	+3.717	.002	.005	3	1
UCEC	SNORD56B →	+0.684	+3.845	.005	.004	3	1
UCEC	RPL23AP4 →	+0.118	+3.717	.001	.005	3	1
UCEC	RPL22P14 →	+0.207	+4.525	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

RTL4 by C11orf94 expression — UCEC

Explore this box plot interactively →