C11orf94

Across TCGA pan-cancer cohorts, C11orf94 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated C11orf94 data layer compared with 1 for mutation status.

The strongest signal is observed in small cell lung cancer (SCLC), where higher C11orf94 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated C11orf94 expression acts as an unfavorable survival marker, although some lineages such as SCLC and HNSC show a favorable association.

SCLC, ACC, and HNSC are the cancer types where C11orf94 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Median	All	0.782	0.418	<.001	85	view →
ACC	DFS	Median	All	0.431	0.733	<.001	59	view →
HNSC	DFS	Median	III,IV	0.677	0.505	.001	52	view →
KICH	OS	Quartile	III,IV	0.343	1.000	.008	33	view →
LGG	DFS	Tertile	All	0.651	0.808	<.001	22	view →
LIHC	OS	Tertile	All	0.469	0.623	.011	14	view →
BLCA	DFS	Median	III,IV	0.107	0.353	.006	10	view →
LAML	DFS	Quartile	All	0.359	0.671	.021	10	view →
COAD	DFS	Quartile	IV	0.587	0.240	.025	8	view →
SARC	OS	Median	All	0.628	0.336	.001	8	view →
KIRC	DFS	Median	II,III,IV	0.748	0.846	.024	7	view →
MESO	DFS	Quartile	IV	0.228	0.716	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

C11orf94–SCLC (DFS)

Open the SCLC breakdown →