C11orf94

Across TCGA cell cohorts, C11orf94 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,655 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C11orf94-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Regulation of mRNA processing, and Nucleic acid catabolic process. Each is linked with C11orf94 in more than 11 cancer types. Because this analysis shows association rather than direction, both C11orf94-to-partner and partner-to-C11orf94 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by C11orf94-low versus C11orf94-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf94→partner) and Y-score (partner→C11orf94) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.126	+0.249	<.001	.004	2	12
BONE	Regulation of mRNA processing →	+0.071	+0.283	.002	.007	3	11
STOMACH	Nucleic acid catabolic process →	+0.046	+0.369	.001	<.001	3	10
BONE	Negative regulation of RNA splicing →	+0.085	+0.297	<.001	<.001	3	10
SOFT_TISSUE	Regulation of transcription elongation by RNA polymerase II →	+0.046	+0.233	<.001	.004	3	10
BONE	Negative regulation of gene expression, epigenetic →	+0.070	+0.305	.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,655 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by C11orf94 expression — BONE

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