C11orf86

Across TCGA patient cohorts, C11orf86 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf86-associated genes across cancer lineages are CFC1B, SNORD114-7, and MIR100. Each is linked with C11orf86 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf86-to-partner and partner-to-C11orf86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFC1B grouped by C11orf86-low versus C11orf86-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf86→partner) and Y-score (partner→C11orf86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CFC1B →	+0.030	+4.069	<.001	.008	3	1
UCEC	SNORD114-7 →	+0.266	+4.069	.006	.008	3	1
UCEC	MIR100 →	+0.231	+4.437	<.001	.005	3	1
UCEC	RPS7P6 →	+0.188	+2.709	.007	.006	3	1
UCEC	RFKP1 →	+0.114	+3.920	.004	<.001	3	1
UCEC	RPS29P31 →	+0.476	+2.715	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

CFC1B by C11orf86 expression — UCEC

Explore this box plot interactively →