C11orf86

Across TCGA pan-cancer cohorts, C11orf86 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated C11orf86 data layer compared with 1 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher C11orf86 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C11orf86 expression acts as an unfavorable survival marker, although some lineages such as READ and MESO show a favorable association.

UVM, KIRP, and PAAD are the cancer types where C11orf86 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.460	0.745	.003	99	view →
KIRP	DFS	Tertile	All	0.765	0.931	<.001	65	view →
PAAD	OS	Median	All	0.361	0.607	<.001	55	view →
THYM	OS	Tertile	All	0.736	0.974	.006	54	view →
LUAD	OS	Median	All	0.772	0.849	.004	42	view →
ACC	DFS	Tertile	All	0.483	0.816	.002	39	view →
LIHC	OS	Tertile	All	0.690	0.831	.001	39	view →
UCEC	DFS	Median	All	0.554	0.736	<.001	36	view →
KICH	OS	Tertile	All	0.792	0.977	.004	24	view →
READ	OS	Quartile	III,IV	0.912	0.429	.013	17	view →
BRCA	DFS	Median	III,IV	0.737	0.841	.017	15	view →
MESO	DFS	Tertile	IV	0.663	0.164	.022	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

C11orf86–UVM (OS)

Open the UVM breakdown →