C11orf80

Across TCGA cell cohorts, C11orf80 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,815 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C11orf80-associated GO terms across cancer lineages are Protein localization to cytoplasmic stress granule, Flagellated sperm motility, and Sperm motility. Each is linked with C11orf80 in more than 10 cancer types. Because this analysis shows association rather than direction, both C11orf80-to-partner and partner-to-C11orf80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cytoplasmic stress granule grouped by C11orf80-low versus C11orf80-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf80→partner) and Y-score (partner→C11orf80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein localization to cytoplasmic stress granule →	+0.169	+0.946	<.001	.003	3	10
LIVER	Flagellated sperm motility →	-0.116	-1.172	.002	.003	2	11
LIVER	Sperm motility →	-0.116	-1.172	.002	.003	2	11
PANCREAS	Establishment of epithelial cell apical/basal polarity →	-0.169	-0.588	<.001	.008	3	10
SKIN	Regulation of dephosphorylation →	+0.096	+0.759	<.001	<.001	3	9
BREAST	Post-Golgi vesicle-mediated transport →	+0.071	+0.877	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,815 associations by consensus.

Protein localization to cytoplasmic stress granule by C11orf80 expression — LUNG_SCLC

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