C11orf52

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C11orf52 protein abundance is significantly associated with the RNA expression of many other genes, with 9,887 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C11orf52-associated genes across cancer lineages are ILDR1, CAVIN4, and CCN4. Each is linked with C11orf52 in more than 4 cancer types. Because this analysis shows association rather than direction, both C11orf52-to-partner and partner-to-C11orf52 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C11orf52 versus ILDR1 in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf52→partner) and Y-score (partner→C11orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCILDR1 →+0.988+0.755.001.00535
OVCAVIN4 →-0.608-0.865.007.00234
PDACCCN4 →-0.961-0.667<.001<.00134
BRCAELAPOR1 →+1.694+0.851<.001<.00134
HNSCMRAS →-0.740-0.656.001.00134
UCECCHST11 →-0.584-0.662.004.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,887 associations by consensus.

C11orf52 vs ILDR1 — HNSC

Per-sample scatter of C11orf52 vs ILDR1 in HNSC (Pearson r = 0.35).

Explore this scatter interactively →

Exploration