C11orf49

Across TCGA patient cohorts, C11orf49 protein abundance is significantly associated with the RNA expression of many other genes, with 390 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C11orf49-associated genes across cancer lineages are TNRC6B, ST13, and EMC2. Each is linked with C11orf49 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf49-to-partner and partner-to-C11orf49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C11orf49 versus TNRC6B in GBM, with a Pearson correlation of 0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf49→partner) and Y-score (partner→C11orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TNRC6B →	+0.741	+0.634	.004	.001	3	1
GBM	ST13 →	+0.621	+0.433	.005	.003	3	1
GBM	EMC2 →	+0.822	+0.432	.004	.003	3	1
GBM	CAPS →	+1.258	+0.544	.006	<.001	3	1
GBM	ZBTB16 →	+1.109	+0.520	.008	.004	3	1
GBM	C11orf21 →	+0.786	+0.570	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

C11orf49 vs TNRC6B — GBM

Explore this scatter interactively →