C11orf49

Across TCGA cell cohorts, C11orf49 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C11orf49-associated genes across cancer lineages are MMD2, GP9, and OR4F21. Each is linked with C11orf49 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf49-to-partner and partner-to-C11orf49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMD2 grouped by C11orf49-low versus C11orf49-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf49→partner) and Y-score (partner→C11orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	MMD2 →	+0.063	+5.087	<.001	.004	3	1
LARGE_INTESTINE	GP9 →	+0.075	+3.196	.002	.007	3	1
LARGE_INTESTINE	OR4F21 →	+0.156	+3.878	<.001	.003	3	1
LARGE_INTESTINE	C14orf180 →	+0.102	+3.155	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MMD2 by C11orf49 expression — URINARY_TRACT

Explore this box plot interactively →