C11orf21

Across TCGA patient cohorts, C11orf21 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. CESC shows the largest number of these associations.

The most reproducible C11orf21-associated genes across cancer lineages are MIR410, RNY4P9, and RNA5SP79. Each is linked with C11orf21 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf21-to-partner and partner-to-C11orf21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR410 grouped by C11orf21-low versus C11orf21-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf21→partner) and Y-score (partner→C11orf21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR410 →	+0.292	+6.342	<.001	.001	3	1
CESC	RNY4P9 →	+0.439	+5.669	<.001	.003	3	1
CESC	RNA5SP79 →	+0.280	+5.010	.008	.009	3	1
CESC	MT-TS1 →	+0.428	+6.144	<.001	.001	3	1
CESC	PPP1R12BP1 →	+0.022	+5.969	<.001	.002	3	1
CESC	LINC00692 →	+0.041	+6.837	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

MIR410 by C11orf21 expression — CESC

Explore this box plot interactively →