Across TCGA patient cohorts, C10orf99 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf99-associated genes across cancer lineages are RFKP1, MIR6130, and RNA5SP45. Each is linked with C10orf99 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf99-to-partner and partner-to-C10orf99 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf99→partner) and Y-score (partner→C10orf99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RFKP1 →	+0.240	+4.242	<.001	.002	3	2
BRCA	MIR6130 →	+0.268	+7.471	<.001	.008	3	1
BRCA	RNA5SP45 →	+0.437	+6.324	<.001	.001	3	1
BRCA	OR11G1P →	+0.053	+5.841	<.001	.003	3	1
BRCA	LINC02563 →	+0.300	+6.442	<.001	.001	3	1
UCEC	RN7SL248P →	+0.147	+4.722	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

C10orf99 survival (RNA) · tumor vs normal (RNA) · all C10orf99 data types