C10orf88

Across TCGA patient cohorts, C10orf88 mutation is significantly associated with the RNA expression of many other genes, with 2,756 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf88-associated genes across cancer lineages are MIR4494, OR12D1, and RNA5SP56. Each is linked with C10orf88 in more than 2 cancer types. Because this analysis shows association rather than direction, both C10orf88-to-partner and partner-to-C10orf88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4494 grouped by C10orf88-low versus C10orf88-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf88→partner) and Y-score (partner→C10orf88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MIR4494 →	+0.498	+5.219	<.001	.006	3	3
SKCM	OR12D1 →	+0.035	+4.282	<.001	.009	3	3
LUSC	RNA5SP56 →	+0.189	+5.327	<.001	.001	3	3
CESC	POTEH-AS1 →	+0.021	+5.669	<.001	.003	3	2
SKCM	LARP7P4 →	+0.063	+4.614	<.001	.006	3	2
HNSC	RN7SKP10 →	+0.150	+4.578	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,756 associations by consensus.

MIR4494 by C10orf88 expression — READ

Explore this box plot interactively →