C10orf88

Across TCGA pan-cancer cohorts, C10orf88 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated C10orf88 data layer compared with 1 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher C10orf88 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C10orf88 expression acts as an unfavorable survival marker, although some lineages such as LGG and KIRC show a favorable association.

LIHC, ACC, and STAD are the cancer types where C10orf88 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.706	0.843	<.001	97	view →
ACC	DFS	Median	All	0.336	0.813	<.001	71	view →
STAD	DFS	Tertile	All	0.312	0.778	.001	50	view →
LGG	DFS	Tertile	All	0.513	0.320	<.001	44	view →
KIRC	DFS	Quartile	All	0.807	0.493	<.001	40	view →
UVM	DFS	Median	III,IV	0.273	0.703	.006	33	view →
KICH	DFS	Quartile	All	0.657	1.000	.006	24	view →
HNSC	OS	Tertile	All	0.592	0.830	.003	24	view →
BLCA	DFS	Tertile	IV	0.245	0.481	.007	21	view →
THYM	OS	Tertile	All	1.000	0.707	.004	17	view →
DLBC	DFS	Tertile	All	0.546	0.939	.003	11	view →
CESC	DFS	Tertile	III,IV	0.403	0.767	.026	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

C10orf88–LIHC (OS)

Open the LIHC breakdown →