C10orf88

Across TCGA cell cohorts, C10orf88 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,055 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C10orf88-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Microtubule polymerization, and Regulation of sister chromatid cohesion. Each is linked with C10orf88 in more than 16 cancer types. Because this analysis shows association rather than direction, both C10orf88-to-partner and partner-to-C10orf88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by C10orf88-low versus C10orf88-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf88→partner) and Y-score (partner→C10orf88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.110	+0.806	<.001	<.001	3	17
STOMACH	Microtubule polymerization →	+0.120	+0.909	<.001	.001	3	13
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.129	+0.399	<.001	<.001	3	13
BLOOD_Myeloma	Positive regulation of organelle assembly →	+0.064	+0.988	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair →	+0.055	+0.433	<.001	.002	3	12
LIVER	Phosphatidylinositol dephosphorylation →	+0.101	+0.612	<.001	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,055 associations by consensus.

Viral translational termination-reinitiation by C10orf88 expression — UPPER_AERODIGESTIVE_TRACT

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