C10orf88

Across TCGA cell cohorts, C10orf88 mutation is significantly associated with the drug of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C10orf88-associated genes across cancer lineages are LCL161, GSK2801, and Venotoclax. Each is linked with C10orf88 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf88-to-partner and partner-to-C10orf88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCL161 grouped by C10orf88-low versus C10orf88-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf88→partner) and Y-score (partner→C10orf88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCL161 →	+0.393	+2.646	.015	.047	3	1
LARGE_INTESTINE	GSK2801 →	+0.412	+2.678	.008	.037	3	1
LARGE_INTESTINE	Venotoclax →	+0.157	+2.722	.049	.040	2	2
LARGE_INTESTINE	SGC-CBP30 →	+0.327	+2.649	.020	.046	2	1
LARGE_INTESTINE	GSK690693 →	+0.684	+2.652	.006	.045	2	1
LARGE_INTESTINE	CZC24832 →	+0.267	+2.646	.040	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

LCL161 by C10orf88 expression — LARGE_INTESTINE

Explore this box plot interactively →