C10orf143

Across TCGA pan-cancer cohorts, C10orf143 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated C10orf143 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher C10orf143 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated C10orf143 expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUAD show a favorable association.

KIRP, UVM, and LUAD are the cancer types where C10orf143 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	1.000	0.491	<.001	71	view →
UVM	DFS	Median	II,III,IV	0.322	0.607	<.001	70	view →
LUAD	DFS	Tertile	All	0.874	0.747	<.001	67	view →
HNSC	OS	Quartile	All	0.847	0.691	.001	58	view →
LGG	DFS	Median	All	0.470	0.329	<.001	44	view →
PAAD	DFS	Quartile	All	0.686	0.332	<.001	40	view →
MESO	OS	Median	All	0.481	0.305	.009	35	view →
ACC	DFS	Median	IV	0.495	0.066	.001	30	view →
LUSC	OS	Median	III,IV	0.761	0.536	.001	18	view →
KIRC	OS	Median	All	0.840	0.769	.006	17	view →
COAD	DFS	Quartile	IV	0.173	0.500	.015	15	view →
ESCA	OS	Tertile	II,III,IV	0.634	0.350	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

C10orf143–KIRP (DFS)

Open the KIRP breakdown →