C10orf120

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C10orf120 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf120-associated genes across cancer lineages are 4E-BP1, CD49b, and EGFR_pY1068. Each is linked with C10orf120 in more than 2 cancer types. Because this analysis shows association rather than direction, both C10orf120-to-partner and partner-to-C10orf120 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf120→partner) and Y-score (partner→C10orf120) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC4E-BP1 →+0.427+3.351<.001.00533
SKCMCD49b →-0.259-1.874.007.04933
UCECEGFR_pY1068 →-0.336-3.700.003.00132
UCECGSK-3_pS9 →-0.393-2.321.037.03432
UCECPCNA →+0.329+2.321.001.03432
UCECRab25 →-0.537-2.584<.001.01132
Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

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