Across TCGA patient cohorts, C10orf105 mutation is significantly associated with the RNA expression of many other genes, with 152 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf105-associated genes across cancer lineages are RN7SKP115, RN7SKP128, and RNU6-996P. Each is linked with C10orf105 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf105-to-partner and partner-to-C10orf105 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf105→partner) and Y-score (partner→C10orf105) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP115 →	+0.364	+2.465	.006	.005	3	2
COAD	RN7SKP128 →	+0.538	+7.741	<.001	.009	3	1
COAD	RNU6-996P →	+0.357	+7.741	<.001	.009	3	1
COAD	MIR539 →	+0.601	+7.741	<.001	.009	3	1
COAD	MIR655 →	+0.383	+7.741	<.001	.009	3	1
COAD	RNU6-1246P →	+1.377	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 152 associations by consensus.

Exploration

C10orf105 survival (RNA) · tumor vs normal (RNA) · all C10orf105 data types