BVES

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BVES protein abundance is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BVES-associated genes across cancer lineages are RHOT1, RPS4Y1, and COX7B. Each is linked with BVES in more than 1 cancer types. Because this analysis shows association rather than direction, both BVES-to-partner and partner-to-BVES results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BVES versus RHOT1 in PDAC, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BVES→partner) and Y-score (partner→BVES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACRHOT1 →+0.345+0.884.001.00511
PDACRPS4Y1 →-6.575-0.884.005.00511
PDACCOX7B →+0.320+0.884.002.00511
PDACKREMEN2 →+0.175+0.884.004.00511
PDACSYT6 →-0.335-0.884.009.00511
PDACTPM3 →+0.379+0.884.005.00511
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

BVES vs RHOT1 — PDAC

Per-sample scatter of BVES vs RHOT1 in PDAC (Pearson r = 0.80).

Explore this scatter interactively →

Exploration