BVES

Across TCGA pan-cancer cohorts, BVES RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated BVES data layer compared with 4 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher BVES RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BVES expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

BLCA, ACC, and LGG are the cancer types where BVES RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.446	0.606	.001	104	view →
ACC	DFS	Median	III,IV	0.276	0.749	.003	54	view →
LGG	OS	Median	All	0.365	0.529	<.001	51	view →
OV	DFS	Tertile	All	0.499	0.611	.003	46	view →
KIRC	DFS	Median	All	0.873	0.719	.002	44	view →
LAML	DFS	Tertile	All	0.195	0.536	.004	36	view →
KIRP	DFS	Tertile	III,IV	0.143	0.833	.001	34	view →
UCS	OS	Median	III,IV	0.779	0.396	.001	24	view →
SKCM	DFS	Median	II,III,IV	0.635	0.499	.001	23	view →
SCLC	DFS	Tertile	IV	0.119	0.498	.003	18	view →
THCA	OS	Tertile	All	0.987	1.000	.009	17	view →
LUSC	OS	Quartile	III,IV	0.399	0.687	.011	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

BVES–BLCA (DFS)

Open the BLCA breakdown →