BVES

Across TCGA patient cohorts, BVES mutation is significantly associated with the RNA expression of many other genes, with 2,399 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BVES-associated genes across cancer lineages are RNA5SP238, OR7E97P, and RNU1-35P. Each is linked with BVES in more than 2 cancer types. Because this analysis shows association rather than direction, both BVES-to-partner and partner-to-BVES results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP238 grouped by BVES-low versus BVES-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BVES→partner) and Y-score (partner→BVES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP238 →	+0.219	+4.393	<.001	.008	3	3
SKCM	OR7E97P →	+0.015	+4.485	<.001	.004	3	2
COAD	RNU1-35P →	+0.736	+5.212	<.001	.007	3	2
COAD	RNU1-109P →	+1.093	+5.435	<.001	.005	3	2
COAD	SLC30A6P1 →	+0.464	+5.516	<.001	.004	3	2
COAD	SCAND3P1 →	+0.191	+5.080	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,399 associations by consensus.

RNA5SP238 by BVES expression — LUSC

Explore this box plot interactively →