BUD23

Across TCGA patient cohorts, BUD23 protein abundance is significantly associated with the RNA expression of many other genes, with 11,869 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BUD23-associated genes across cancer lineages are ACTR3B, ORC5, and DNAJC2. Each is linked with BUD23 in more than 8 cancer types. Because this analysis shows association rather than direction, both BUD23-to-partner and partner-to-BUD23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BUD23 versus ACTR3B in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BUD23→partner) and Y-score (partner→BUD23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ACTR3B →	+0.722	+0.510	<.001	<.001	3	9
HNSC	ORC5 →	+0.603	+0.251	.001	.001	3	8
HNSC	DNAJC2 →	+0.720	+0.253	.001	.001	2	8
GBM	RSBN1L →	+0.559	+0.506	<.001	<.001	3	7
BRCA	DBF4 →	+0.604	+0.396	<.001	<.001	3	7
HNSC	PMPCB →	+0.560	+0.226	.002	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,869 associations by consensus.

BUD23 vs ACTR3B — LSCC

Explore this scatter interactively →