BTNL9

Across TCGA patient cohorts, BTNL9 mutation is significantly associated with the RNA expression of many other genes, with 2,072 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTNL9-associated genes across cancer lineages are HMGB1P12, DDX11L16, and MIR3689B. Each is linked with BTNL9 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTNL9-to-partner and partner-to-BTNL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGB1P12 grouped by BTNL9-low versus BTNL9-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTNL9→partner) and Y-score (partner→BTNL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HMGB1P12 →	+0.051	+4.298	<.001	.009	3	3
LUSC	DDX11L16 →	+0.299	+3.902	<.001	.007	3	2
LUSC	MIR3689B →	+0.176	+4.724	<.001	.005	3	2
UCEC	MIR6892 →	+0.359	+2.348	<.001	.001	3	2
UCEC	SGSM3 →	+0.503	+3.716	.002	<.001	3	2
UCEC	AAGAB →	+0.616	+2.949	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,072 associations by consensus.

HMGB1P12 by BTNL9 expression — BRCA

Explore this box plot interactively →