BTN3A3

Across TCGA patient cohorts, BTN3A3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,220 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BTN3A3-associated genes across cancer lineages are PSMB8-AS1, HCP5, and HLA-E. Each is linked with BTN3A3 in more than 8 cancer types. Because this analysis shows association rather than direction, both BTN3A3-to-partner and partner-to-BTN3A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTN3A3 versus PSMB8-AS1 in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN3A3→partner) and Y-score (partner→BTN3A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PSMB8-AS1 →	+0.749	+0.434	<.001	<.001	3	9
LUAD	HCP5 →	+1.030	+0.434	<.001	<.001	3	9
BRCA	HLA-E →	+0.723	+0.442	<.001	<.001	3	8
LUAD	HLA-F →	+1.066	+0.518	<.001	<.001	3	8
LSCC	HLA-B →	+0.952	+0.523	<.001	<.001	3	8
BRCA	APOBEC3H →	+0.891	+0.560	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,220 associations by consensus.

BTN3A3 vs PSMB8-AS1 — BRCA

Explore this scatter interactively →