BTN2A2

Across TCGA pan-cancer cohorts, BTN2A2 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BTN2A2 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BTN2A2 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated BTN2A2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LIHC, and LUSC are the cancer types where BTN2A2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.968	0.624	.009	24	view →
LIHC	OS	Median	II,III,IV	0.118	0.716	.003	15	view →
LUSC	DFS	Median	III,IV	0.200	0.668	.002	9	view →
LGG	DFS	Median	All	0.080	0.826	<.001	6	view →
BLCA	DFS	Median	IV	0.176	0.473	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BTN2A2–UCEC (DFS)

Open the UCEC breakdown →