BTN2A2

Across TCGA patient cohorts, BTN2A2 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTN2A2-associated genes across cancer lineages are Cyclin-E2, eIF4E, and JNK2. Each is linked with BTN2A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BTN2A2-to-partner and partner-to-BTN2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by BTN2A2-low versus BTN2A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN2A2→partner) and Y-score (partner→BTN2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-E2 →	+0.118	+1.321	.036	.029	3	3
UCEC	eIF4E →	+0.171	+2.713	.015	.003	3	2
UCEC	JNK2 →	+0.279	+3.727	<.001	<.001	3	2
UCEC	MEK1 →	+0.446	+2.201	<.001	<.001	3	2
UCEC	PDCD4 →	-0.443	-1.584	.004	.009	3	2
UCEC	ATM →	-0.518	-3.794	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Cyclin-E2 by BTN2A2 expression — UCEC

Explore this box plot interactively →