BTN2A2

Across TCGA cell cohorts, BTN2A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,029 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BTN2A2-associated GO terms across cancer lineages are MHC class I protein complex assembly, Peptide antigen assembly with MHC class I protein complex, and Golgi vesicle transport. Each is linked with BTN2A2 in more than 11 cancer types. Because this analysis shows association rather than direction, both BTN2A2-to-partner and partner-to-BTN2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MHC class I protein complex assembly grouped by BTN2A2-low versus BTN2A2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN2A2→partner) and Y-score (partner→BTN2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MHC class I protein complex assembly →	+0.164	+1.249	<.001	<.001	3	12
BREAST	Peptide antigen assembly with MHC class I protein complex →	+0.164	+1.249	<.001	<.001	3	12
BLOOD_Lymphoma	Golgi vesicle transport →	+0.056	+1.230	<.001	<.001	3	12
BLOOD_Leukemia	Microtubule polymerization →	+0.113	+1.299	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Microtubule polymerization or depolymerization →	+0.122	+1.084	.006	.005	2	12
BREAST	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.126	+1.187	.004	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,029 associations by consensus.

MHC class I protein complex assembly by BTN2A2 expression — BREAST

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