BTN2A2

Across TCGA cell cohorts, BTN2A2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTN2A2-associated genes across cancer lineages are OR52E8, SERPINA7, and USP17L19. Each is linked with BTN2A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTN2A2-to-partner and partner-to-BTN2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52E8 grouped by BTN2A2-low versus BTN2A2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN2A2→partner) and Y-score (partner→BTN2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR52E8 →	+0.020	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	SERPINA7 →	+0.012	+5.813	<.001	<.001	3	1
LUNG_NSCLC_LUAD	USP17L19 →	+0.005	+5.266	<.001	.001	3	1
LARGE_INTESTINE	SIGLEC8 →	+0.013	+3.930	<.001	.003	3	1
LARGE_INTESTINE	PPDPFL →	+0.055	+4.217	<.001	.001	3	1
LARGE_INTESTINE	AMELY →	+0.036	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR52E8 by BTN2A2 expression — OESOPHAGUS

Explore this box plot interactively →