BTN2A1

Across TCGA patient cohorts, BTN2A1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTN2A1-associated genes across cancer lineages are EGFR_pY1068, INPP4B, and Annexin-1. Each is linked with BTN2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTN2A1-to-partner and partner-to-BTN2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by BTN2A1-low versus BTN2A1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN2A1→partner) and Y-score (partner→BTN2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EGFR_pY1068 →	-0.469	-3.000	.003	.034	3	2
COAD	INPP4B →	-0.532	-3.169	.003	.018	3	2
COAD	Annexin-1 →	+0.504	+3.000	.007	.034	3	2
UCEC	HER3_pY1289 →	+0.062	+3.169	.031	.018	3	2
UCEC	Cyclin-B1 →	+0.673	+1.874	<.001	.002	3	2
UCEC	Cyclin-E2 →	+0.162	+1.775	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

EGFR_pY1068 by BTN2A1 expression — COAD

Explore this box plot interactively →