Across TCGA patient cohorts, BTLA protein abundance is significantly associated with the RNA expression of many other genes, with 6,226 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BTLA-associated genes across cancer lineages are FCER2, PTGDS, and VNN2. Each is linked with BTLA in more than 2 cancer types. Because this analysis shows association rather than direction, both BTLA-to-partner and partner-to-BTLA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTLA→partner) and Y-score (partner→BTLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FCER2 →	+0.635	+0.831	<.001	<.001	3	3
LUAD	PTGDS →	+1.074	+0.822	<.001	<.001	3	3
HNSC	VNN2 →	+1.955	+1.223	<.001	<.001	3	3
HNSC	SRGN →	+1.911	+1.223	<.001	<.001	3	3
LUAD	VPREB3 →	+1.719	+1.011	<.001	<.001	3	3
HNSC	ENAM →	+0.649	+1.404	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,226 associations by consensus.

Exploration

BTLA survival (RNA) · tumor vs normal (RNA) · all BTLA data types