Across TCGA patient cohorts, BTLA mutation is significantly associated with the RNA expression of many other genes, with 931 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTLA-associated genes across cancer lineages are RNA5SP24, MIR8061, and SPRYD7P1. Each is linked with BTLA in more than 2 cancer types. Because this analysis shows association rather than direction, both BTLA-to-partner and partner-to-BTLA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTLA→partner) and Y-score (partner→BTLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP24 →	+0.250	+4.884	<.001	.004	3	3
SKCM	MIR8061 →	+0.429	+5.634	<.001	.001	3	2
SKCM	SPRYD7P1 →	+0.079	+4.282	<.001	.009	3	2
SKCM	RNU7-180P →	+0.466	+5.039	<.001	.003	3	2
SKCM	RN7SL292P →	+0.307	+4.877	<.001	<.001	3	2
BLCA	RNA5SP139 →	+0.869	+4.208	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 931 associations by consensus.

Exploration

BTLA survival (RNA) · tumor vs normal (RNA) · all BTLA data types