BTF3P5

Across TCGA pan-cancer cohorts, BTF3P5 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated BTF3P5 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher BTF3P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BTF3P5 expression acts as an unfavorable survival marker, although some lineages such as CESC and KIRC show a favorable association.

KICH, CESC, and KIRC are the cancer types where BTF3P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Quartile	II,III,IV	0.466	1.000	<.001	68	view →
CESC	DFS	Tertile	III,IV	0.726	0.319	.006	42	view →
KIRC	DFS	Tertile	III,IV	0.663	0.241	.001	40	view →
LIHC	DFS	Quartile	All	0.176	0.506	.004	35	view →
UCS	OS	Quartile	III,IV	0.215	0.690	.005	30	view →
COAD	OS	Median	All	0.680	0.413	<.001	26	view →
BRCA	OS	Quartile	II,III,IV	0.942	0.874	.005	23	view →
SKCM	OS	Median	III,IV	0.490	0.290	.008	22	view →
LUSC	DFS	Median	II,III,IV	0.691	0.487	<.001	22	view →
STAD	DFS	Tertile	IV	0.177	0.720	.007	20	view →
ACC	OS	Quartile	II,III,IV	0.696	0.961	.009	17	view →
OV	OS	Quartile	II,III,IV	0.253	0.368	.017	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

BTF3P5–KICH (DFS)

Open the KICH breakdown →