BTF3P5

Across TCGA pan-cancer cohorts, BTF3P5 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of BTF3P5’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where BTF3P5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BTF3P5 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

COAD, KIRC, and LUAD are the cancer types where BTF3P5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BTF3P5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.515	<.001	4	view →
KIRC	Female	All	+0.204	<.001	4	view →
LUAD	All	All	+0.257	.002	3	view →
BLCA	Male	III,IV	+0.348	.014	2	view →
LUSC	Male	All	+0.213	.002	2	view →
PRAD	All	All	+0.134	.026	2	view →
LIHC	All	All	+0.108	.011	2	view →
STAD	All	All	−0.268	.040	1	view →
KIRP	Male	II,III,IV	+0.194	.038	1	view →
HNSC	Male	All	+0.154	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

BTF3P5–COAD

Open the COAD breakdown →