BTC

Across TCGA patient cohorts, BTC RNA expression is significantly associated with the protein abundance of many other proteins, with 10,359 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BTC-associated proteins across cancer lineages are TLR3, TMEM63A, and PSMB5. Each is linked with BTC in more than 3 cancer types. Because this analysis shows association rather than direction, both BTC-to-partner and partner-to-BTC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTC versus TLR3 in UCEC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BTC→partner) and Y-score (partner→BTC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TLR3 →	+0.483	+0.876	<.001	<.001	3	4
HNSC	TMEM63A →	+0.480	+1.027	<.001	<.001	3	4
CCRCC	PSMB5 →	-0.366	-0.585	.002	.007	3	4
PDAC	SHROOM3_S439 →	+0.539	+0.631	.001	<.001	3	4
UCEC	FSCN1 →	-0.508	-0.832	<.001	.006	3	4
UCEC	MAP9_S79 →	+0.529	+0.868	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,359 associations by consensus.

BTC vs TLR3 — UCEC

Explore this scatter interactively →