BTC

Across TCGA patient cohorts, BTC protein abundance is significantly associated with the protein abundance of many other proteins, with 3,359 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible BTC-associated proteins across cancer lineages are TGS1_S298, CEP164_S319, and EIF4B_S504. Each is linked with BTC in more than 1 cancer types. Because this analysis shows association rather than direction, both BTC-to-partner and partner-to-BTC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTC versus TGS1_S298 in LSCC, with a Pearson correlation of -0.53.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BTC→partner) and Y-score (partner→BTC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TGS1_S298 →	-1.570	-0.777	<.001	.001	3	2
LSCC	CEP164_S319 →	+0.955	+0.428	<.001	.002	3	2
LSCC	EIF4B_S504 →	-0.754	-0.678	.002	<.001	3	2
UCEC	TFRC →	-0.854	-0.483	<.001	.003	3	2
LUAD	UTP23 →	-0.507	-0.483	<.001	.001	3	2
LUAD	ZC3H15 →	-0.181	-0.340	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,359 associations by consensus.

BTC vs TGS1_S298 — LSCC

Explore this scatter interactively →