BTC

Across TCGA cell cohorts, BTC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,452 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible BTC-associated GO terms across cancer lineages are Membrane assembly, Vesicle budding from membrane, and Biological process involved in interaction with host. Each is linked with BTC in more than 9 cancer types. Because this analysis shows association rather than direction, both BTC-to-partner and partner-to-BTC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane assembly grouped by BTC-low versus BTC-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTC→partner) and Y-score (partner→BTC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Membrane assembly →	+0.100	+1.345	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Vesicle budding from membrane →	+0.063	+0.692	.001	.007	3	10
BONE	Biological process involved in interaction with host →	+0.086	+0.241	<.001	.009	3	10
URINARY_TRACT	Positive regulation of keratinocyte proliferation →	+0.280	+2.058	<.001	<.001	3	9
PANCREAS	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.184	+1.030	<.001	<.001	3	9
OVARY	Protein exit from endoplasmic reticulum →	+0.092	+1.165	<.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,452 associations by consensus.

Membrane assembly by BTC expression — STOMACH

Explore this box plot interactively →