Across TCGA pan-cancer cohorts, BTBD9-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of BTBD9-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where BTBD9-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types BTBD9-AS1 is over-expressed in tumor, although a few such as LUSC and KIRP show the opposite, repressed pattern.

LUSC, BRCA, and KIRP are the cancer types where BTBD9-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BTBD9-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−0.200	<.001	5	view →
BRCA	All	All	+0.218	.020	4	view →
KIRP	Male	All	−0.076	.008	2	view →
THCA	Female	All	−0.074	.010	2	view →
LIHC	Female	All	+0.030	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: BTBD9-AS1 RNA expression & survival · all BTBD9-AS1 data types