BTBD7

Across TCGA cell cohorts, BTBD7 mutation is significantly associated with the RNA expression of many other genes, with 818 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTBD7-associated genes across cancer lineages are TEX55, OR6B2, and OR2AK2. Each is linked with BTBD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD7-to-partner and partner-to-BTBD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX55 grouped by BTBD7-low versus BTBD7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD7→partner) and Y-score (partner→BTBD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	TEX55 →	+0.060	+3.113	.006	.004	3	2
OVARY	OR6B2 →	+0.031	+3.624	.004	.005	3	2
OVARY	OR2AK2 →	+0.046	+2.859	<.001	.008	3	2
OVARY	CNR2 →	+0.016	+4.539	<.001	.002	3	2
OVARY	OR2L13 →	+0.807	+3.906	<.001	.002	3	2
BLOOD_Leukemia	PRAC1 →	+0.552	+3.884	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 818 associations by consensus.

TEX55 by BTBD7 expression — OVARY

Explore this box plot interactively →