Across TCGA cell cohorts, BTBD19 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTBD19-associated genes across cancer lineages are XAGE5, IFNA17, and SYCN. Each is linked with BTBD19 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD19-to-partner and partner-to-BTBD19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD19→partner) and Y-score (partner→BTBD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	XAGE5 →	+0.255	+5.196	<.001	.005	3	1
OVARY	IFNA17 →	+0.020	+5.807	<.001	.001	3	1
BLOOD_Leukemia	SYCN →	+0.035	+4.539	<.001	.007	3	1
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	LRRC3C →	+0.333	+3.658	<.001	.005	3	1
LARGE_INTESTINE	MAGEB1 →	+0.187	+3.878	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

BTBD19 survival (RNA) · tumor vs normal (RNA) · all BTBD19 data types