Across TCGA cell cohorts, BTBD17 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible BTBD17-associated genes across cancer lineages are RBMY1F, OR5T2, and CASP12. Each is linked with BTBD17 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD17-to-partner and partner-to-BTBD17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD17→partner) and Y-score (partner→BTBD17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	RBMY1F →	+0.782	+4.643	<.001	.004	3	1
LUNG_SCLC	OR5T2 →	+0.015	+4.643	<.001	.004	3	1
LUNG_SCLC	CASP12 →	+0.138	+4.269	<.001	.005	3	1
LUNG_SCLC	RBMY1A1 →	+1.434	+4.044	<.001	.009	3	1
STOMACH	BMP15 →	+0.032	+4.285	<.001	.007	3	1
STOMACH	RTP1 →	+0.013	+4.129	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

BTBD17 survival (RNA) · tumor vs normal (RNA) · all BTBD17 data types