BTBD11

Across TCGA patient cohorts, BTBD11 mutation is significantly associated with the RNA expression of many other genes, with 4,607 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTBD11-associated genes across cancer lineages are C9orf50, UQCRC1, and PSMD9. Each is linked with BTBD11 in more than 3 cancer types. Because this analysis shows association rather than direction, both BTBD11-to-partner and partner-to-BTBD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf50 grouped by BTBD11-low versus BTBD11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD11→partner) and Y-score (partner→BTBD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C9orf50 →	-0.365	-2.321	.002	<.001	3	4
UCEC	UQCRC1 →	+0.279	+2.153	.006	<.001	3	4
UCEC	PSMD9 →	+0.309	+1.632	.001	<.001	3	4
COAD	GOT1 →	+0.387	+2.249	.007	.006	3	4
UCEC	AURKB →	+0.542	+2.258	.001	<.001	3	3
UCEC	AEN →	+0.566	+1.653	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,607 associations by consensus.

C9orf50 by BTBD11 expression — UCEC

Explore this box plot interactively →