BTBD11

Across TCGA cell cohorts, BTBD11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,301 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BTBD11-associated GO terms across cancer lineages are Release of cytochrome c from mitochondria, Negative regulation of protein catabolic process, and Regulation of protein localization to nucleus. Each is linked with BTBD11 in more than 9 cancer types. Because this analysis shows association rather than direction, both BTBD11-to-partner and partner-to-BTBD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Release of cytochrome c from mitochondria grouped by BTBD11-low versus BTBD11-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD11→partner) and Y-score (partner→BTBD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Release of cytochrome c from mitochondria →	+0.124	+1.425	<.001	<.001	3	10
STOMACH	Negative regulation of protein catabolic process →	+0.089	+1.634	<.001	.001	3	9
LUNG_SCLC	Regulation of protein localization to nucleus →	+0.060	+1.908	<.001	<.001	3	9
OVARY	Cell-substrate junction organization →	+0.134	+1.330	<.001	<.001	3	8
STOMACH	Regulation of intrinsic apoptotic signaling pathway →	+0.060	+1.456	.005	.006	3	8
KIDNEY	Protein localization to membrane raft →	+0.240	+1.679	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,301 associations by consensus.

Release of cytochrome c from mitochondria by BTBD11 expression — LARGE_INTESTINE

Explore this box plot interactively →