BTBD11

Across TCGA cell cohorts, BTBD11 mutation is significantly associated with the RNA expression of many other genes, with 700 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTBD11-associated genes across cancer lineages are TMSB4Y, AWAT2, and PRAMEF10. Each is linked with BTBD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTBD11-to-partner and partner-to-BTBD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMSB4Y grouped by BTBD11-low versus BTBD11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD11→partner) and Y-score (partner→BTBD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMSB4Y →	+1.123	+2.807	<.001	.004	3	2
CNS	AWAT2 →	+0.222	+3.832	<.001	.007	3	1
CNS	PRAMEF10 →	+0.231	+4.169	<.001	.008	3	1
BREAST	GAGE12F →	+0.715	+5.169	<.001	.005	3	1
BLOOD_Lymphoma	REG3G →	+0.026	+4.867	.004	.009	3	1
LUNG_SCLC	ATP6V1G3 →	+0.242	+3.099	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 700 associations by consensus.

TMSB4Y by BTBD11 expression — LARGE_INTESTINE

Explore this box plot interactively →