BTBD11

Across TCGA cell cohorts, BTBD11 mutation is significantly associated with the mutation status of many other genes, with 5,044 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTBD11-associated genes across cancer lineages are TNRC6C, ABCC11, and PCNX3. Each is linked with BTBD11 in more than 5 cancer types. Because this analysis shows association rather than direction, both BTBD11-to-partner and partner-to-BTBD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNRC6C grouped by BTBD11-low versus BTBD11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTBD11→partner) and Y-score (partner→BTBD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TNRC6C →	+3.969	+3.969	.002	.002	1	6
LARGE_INTESTINE	ABCC11 →	+3.129	+2.956	<.001	<.001	1	6
LARGE_INTESTINE	PCNX3 →	+2.321	+3.169	<.001	<.001	1	6
BLOOD_Lymphoma	DOCK7 →	+3.969	+3.969	.002	.002	1	5
BLOOD_Lymphoma	OBSL1 →	+2.832	+4.714	<.001	<.001	1	5
BLOOD_Lymphoma	SNRNP200 →	+3.384	+4.169	<.001	<.001	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,044 associations by consensus.

TNRC6C by BTBD11 expression — BLOOD_Lymphoma

Explore this box plot interactively →