BST2

Across TCGA patient cohorts, BST2 mutation is significantly associated with the RNA expression of many other genes, with 91 significant associations in total. COAD shows the largest number of these associations.

The most reproducible BST2-associated genes across cancer lineages are RNA5SP502, RN7SL191P, and MIR378E. Each is linked with BST2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BST2-to-partner and partner-to-BST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP502 grouped by BST2-low versus BST2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BST2→partner) and Y-score (partner→BST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP502 →	+0.284	+6.087	<.001	.002	3	2
UCEC	RN7SL191P →	+0.302	+3.666	<.001	.004	3	2
COAD	MIR378E →	+1.372	+6.721	<.001	<.001	3	2
UCEC	NUTF2P8 →	+0.133	+3.567	.002	.005	3	1
UCEC	MIR98 →	+0.755	+4.216	<.001	<.001	3	1
COAD	OR4F21 →	+0.103	+5.080	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

RNA5SP502 by BST2 expression — LUAD

Explore this box plot interactively →