BST2

Across TCGA cell cohorts, BST2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,304 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BST2-associated GO terms across cancer lineages are Regulation of intracellular transport of viral material, Negative regulation of viral genome replication, and Negative regulation of viral process. Each is linked with BST2 in more than 15 cancer types. Because this analysis shows association rather than direction, both BST2-to-partner and partner-to-BST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular transport of viral material grouped by BST2-low versus BST2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BST2→partner) and Y-score (partner→BST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of intracellular transport of viral material →	+0.342	+4.605	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of viral genome replication →	+0.175	+3.469	<.001	<.001	3	16
PANCREAS	Negative regulation of viral process →	+0.177	+4.403	<.001	<.001	3	16
KIDNEY	Negative regulation of cytokine production involved in immune response →	+0.262	+4.046	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Defense response to virus →	+0.092	+5.241	.001	.001	3	15
LIVER	Response to interferon-beta →	+0.150	+4.612	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,304 associations by consensus.

Regulation of intracellular transport of viral material by BST2 expression — BREAST

Explore this box plot interactively →