BSPRY

Across TCGA patient cohorts, BSPRY protein abundance is significantly associated with the RNA expression of many other genes, with 16,560 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BSPRY-associated genes across cancer lineages are HDHD3, WDR31, and HSDL2. Each is linked with BSPRY in more than 8 cancer types. Because this analysis shows association rather than direction, both BSPRY-to-partner and partner-to-BSPRY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BSPRY versus HDHD3 in OV, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSPRY→partner) and Y-score (partner→BSPRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HDHD3 →	+0.952	+1.139	<.001	<.001	3	9
BRCA	WDR31 →	+0.954	+0.627	<.001	<.001	3	8
UCEC	HSDL2 →	+0.770	+0.703	<.001	<.001	3	7
OV	AK7 →	+1.151	+0.823	<.001	<.001	3	7
BRCA	ALAD →	+0.831	+0.685	<.001	<.001	3	7
BRCA	OCLN →	+0.823	+0.604	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,560 associations by consensus.

BSPRY vs HDHD3 — OV

Explore this scatter interactively →