Across TCGA patient cohorts, BSPH1 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BSPH1-associated genes across cancer lineages are TIGAR, Bax, and p27_pT198. Each is linked with BSPH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BSPH1-to-partner and partner-to-BSPH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BSPH1→partner) and Y-score (partner→BSPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIGAR →	+0.180	+3.026	.041	.019	3	1
UCEC	Bax →	+0.362	+2.817	.009	.036	3	1
UCEC	p27_pT198 →	+0.133	+3.000	.031	.037	1	1
UCEC	p62 Lck ligand →	+0.684	+3.000	<.001	.037	1	1
UCEC	TFRC →	+0.607	+3.000	.048	.037	1	1
UCEC	Tuberin →	+0.523	+3.000	<.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

BSPH1 survival (RNA) · tumor vs normal (RNA) · all BSPH1 data types