BSN

Across TCGA pan-cancer cohorts, BSN mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated BSN data layer compared with 25 for mass-spec protein and 16 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher BSN mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated BSN expression acts as an unfavorable survival marker.

PDAC and UCEC are the cancer types where BSN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.555	0.769	.032	10	view →
UCEC	OS	Median	All	0.657	1.000	.033	8	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

BSN–PDAC (OS)

Open the PDAC breakdown →