BSN

Across TCGA pan-cancer cohorts, BSN RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BSN’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where BSN RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BSN is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

LIHC, THCA, and KIRC are the cancer types where BSN tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BSN RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.438	<.001	7	view →
THCA	All	II,III,IV	−0.306	<.001	7	view →
KIRC	Male	All	−0.119	.001	6	view →
KICH	All	All	+0.520	<.001	5	view →
KIRP	Female	All	+0.476	.016	3	view →
READ	All	All	−0.210	.016	2	view →
CHOL	All	All	+0.270	.013	1	view →
STAD	Male	IV	+0.209	.034	1	view →
LUAD	Female	II,III,IV	−0.160	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

BSN–LIHC

Open the LIHC breakdown →